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Their therapeutic use for prevention of cardio-embolic troubles was validated in latest big period III trials, demonstrating their non-inferiority, and in some cases superiority, in a few circumstances, to warfarin [5,six,7].PLOS One particular | DOI:10.1371/journal.pone.0126512 May well fourteen,two /Efficacy and Protection of NOACs in RFCA of AFTherefore, usage of NOACs is at the moment encourag