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Bcl-xL promoter is made up of two WT1 binding web-sites 5'-GCGGGGGAGC-3' and 5'GAGCGGGAGT-3', which might be comparable to the consensus WTE motif 5'-GCGTGGGAGT-3' [12] at positions -307 to -298 and -301 to -292 upstream of your transcription start off web site of BclxL gene (Fig 5A still left). Bcl-2 promoter also consists of five WT1 binding web sites along with the consensus sequence 5'-GNGNGGG